Name: | Testosterone Propionate |
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PubChem Compound ID: | 5701990 |
Description: | An ester of TESTOSTERONE with a propionate substitution at the 17-beta position. |
Molecular formula: | C22H32O3 |
Molecular weight: | 344.488 g/mol |
Synonyms: |
KBioGR_000428; DivK1c_000748; KBio1_000748; KBio2_001739; KBio2_004307; Spectrum2_001246; Spectrum4_000104; NINDS_000748; Spectrum_001259; KBio2_006875.
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Name: | Testosterone Propionate |
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Name (isomeric): | DB01420 |
Drug Type: | small molecule |
Description: | An ester of TESTOSTERONE with a propionate substitution at the 17-beta position. |
Brand: | Agovirin, Testex |
Category: | Androgens |
CAS number: | 57-85-2 |
Indication: | Testosterone propionate is an anabolic steroid and a short ester form of testosterone that becomes active in the body. It is often used for muscle mass building. |
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Pharmacology: |
Testosterone is a steroid hormone from the androgen group. Testosterone is primarily secreted from the testes of males. In females, it is produced in the ovaries, adrenal glands and by conversion of adrostenedione in the periphery. It is the principal male sex hormone and an anabolic steroid. In both males and females, it plays key roles in health ...
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Mechanism of Action: |
The effects of testosterone in humans and other vertebrates occur by way of two main mechanisms: by activation of the androgen receptor (directly or as DHT), and by conversion to estradiol and activation of certain estrogen receptors. Free testosterone (T) is transported into the cytoplasm of target tissue cells, where it can bind to the androgen r...
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Protein binding: | 40% of testosterone in plasma is bound to sex hormone-binding globulin and 2% remains unbound and the rest is bound to albumin and other proteins. |
Biotransformation: | Testosterone propionate is rapidly hydrolysed into testosterone. Testosterone is metabolized to 17-keto steroids through two different pathways. The major active metabolites are estradiol and dihydrotestosterone (DHT). |
Route of elimination: | About 90% of a dose of testosterone given intramuscularly is excreted in the urine as glucuronic and sulfuric acid conjugates of testosterone and its metabolites; about 6% of a dose is excreted in the feces, mostly in the unconjugated form. |
Toxicity: | Side effects include amnesia, anxiety, discolored hair, dizziness, dry skin, hirsutism, hostility, impaired urination, paresthesia, penis disorder, peripheral edema, sweating, and vasodilation. |
Affected organisms: | Humans and other mammals |
Drug interaction: |
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